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Biochemistry. Guided tour to the heart of RISC Request PDF

    https://www.researchgate.net/publication/225044684_Biochemistry_Guided_tour_to_the_heart_of_RISC
    Request PDF Biochemistry. Guided tour to the heart of RISC How do eukaryotic cells use small RNAs to control the expression levels of proteins? The answer is of interest both to basic ...

Biochemistry. Guided tour to the heart of RISC.

    https://www.ncbi.nlm.nih.gov/pubmed/22628640
    May 25, 2012 · Biochemistry. Guided tour to the heart of RISC. Kaya E(1), Doudna JA. Author information: (1)Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. Comment on Science. 2012 May 25;336(6084):1037-40. PMID: 22628640 [PubMed - indexed for MEDLINE] Publication Types: CommentCited by: 8

Guided Tour to the Heart of RISC Science

    https://science.sciencemag.org/content/336/6084/985.full
    May 25, 2012 · Guided Tour to the Heart of RISC. Emine Kaya 1, Jennifer A. Doudna 1, 2, 3, 4. 1 Department of Molecular and Cell Biology. 2 Howard Hughes Medical Institute, University of …Cited by: 8

Biochemistry and physiology of cardiac muscle - Medicine

    https://www.medicinejournal.co.uk/article/S1357-3039(10)00082-4/abstract
    The heart is composed of muscle cells (cardiomyocytes) that account for most of the heart mass and generate its pumping force. Other cell types (fibroblasts, vascular endothelial cells, vascular smooth muscle cells) and the extracellular matrix also play key roles in cardiac function, both in health and in disease. Excitation–contraction coupling links the electrical activation of ...Cited by: 3

Structural Biochemistry/Nucleic Acid/RNA/Interference RNA ...

    https://en.wikibooks.org/wiki/Structural_Biochemistry/Nucleic_Acid/RNA/Interference_RNA
    The Slicer model is another for RISC activation where the passenger strand is cleaved into fragments leaving the guide strand to create an activated RISC. [2] Thought to first be around about a billion years ago. siRNA found to be in humans, plants and single cell organisms.

BIOCHEMISTRY of CARDIOVASCULAR SYSTEM authorSTREAM

    http://www.authorstream.com/Presentation/oktokto-1141227-biochemistry-of-cardiovascular-system/
    Fig 1. The energy the heart uses to perform pumping the blood is generated through the hydrolysis of ATP to ADP and Pi. ATP constantly generated by the mitochondria that are abundant in heart muscle cells with small amount relatively: 5 umols/g. ATP turn over rate in ATP pool is very fast : 10-15 sec.

The crystal structure of human Argonaute2. - Abstract ...

    https://europepmc.org/abstract/MED/22539551
    Apr 26, 2012 · Guided tour to the heart of RISC. " Science. 2012 May 25;336(6084):985-6. Share this article Share with email Share with twitter Share with linkedin Share with facebook

Loss of silencing activity caused by 5′-terminal ...

    https://link.springer.com/article/10.1007/s11426-013-5032-4
    Dec 19, 2013 · In this study, a series of 5′-phosphorylated siRNAs with d-/l-isonucleotide (isoNA) or locked nucleic acid (LNA) incorporated at the 5′-terminus were synthesized. It was found that after incorporating either isoNA or LNA at the 5′-terminus of the antisense strand or sense strand, the silencing activity of modified strands has been inhibited, which cannot be recovered by phosphorylation ...

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